- Division Resurgence main missions are the primary way to gain XP and unlock the full NYC map.
- Tactical Cover is non-negotiable; staying out in the open during campaign missions leads to rapid desynchronization.
- Resource Gathering for NPCs like Kelly and Doc O'Neal is required to progress through specific story bottlenecks.
- Signature Abilities should be reserved for faction leaders or "Heavy" armored units encountered at the end of mission stages.
The Division Resurgence main missions form the essential backbone of your career as a Strategic Homeland Division agent in post-crisis New York. These missions are not merely combat encounters; they are narrative-driven operations that task you with restoring the city's infrastructure while battling ruthless factions. Navigating the Division Resurgence main missions requires a deep understanding of tactical positioning, specialized gear, and the unique behaviors of enemies like the Freemen and the Cleaners. Whether you are investigating the lethal diylene glycol poisoning in the local water supply or disrupting illicit arms deals in the open world, the campaign offers a high-stakes experience tailored for mobile precision. In this 2026 guide, we break down the core mission structures, provide walkthroughs for critical story arcs, and offer expert tips to ensure your agent survives the toughest encounters the city has to offer.
Early Campaign Progression and Narrative Arcs
The initial phase of the campaign focuses on re-establishing a foothold in the city. You will frequently interact with key NPCs at the Trinity Church and other safe houses to receive your objectives. The early missions emphasize resource recovery and settlement defense, teaching you the fundamental mechanics of the game.
Video Highlights:
- Resource Acquisition: Learning how to scavenge electrical components from the Freemen.
- Settlement Defense: Protecting local survivors from "wannabe pirates" and looters.
- Tactical Positioning: Using the environment to find the perfect angle for suppressing fire.
| Mission Phase | Primary Objective | Key Faction | Difficulty |
|---|---|---|---|
| Initial Contact | Secure Trinity Church | Rioters | Low |
| Grid Restoration | Retrieve electrical parts | Freemen | Medium |
| Water Crisis | Inspect distribution filters | Cleaners | High |
| Arms Lockdown | Impound illicit weapons | Mixed | Medium |
When hunting for electrical components, look for "Freemen" caches. These enemies tend to hoard supplies like chipmunks, and clearing their small outposts is the fastest way to complete Kelly's early-game requests.
The Water Distribution Crisis Walkthrough
One of the most critical arcs in the Division Resurgence main missions involves the deliberate poisoning of the city's water supply. Doc O'Neal identifies diylene glycol—a byproduct of biodiesel production—as the culprit. This mission arc transitions from simple investigation to high-intensity combat against the Cleaners.
Consult Doc O'Neal
Visit the lab after the Trinity Church defense to learn about the seizures and myopathy affecting the patients.
Locate Moss
Head to the local water distribution facility to find Moss, who is inspecting the filters. Be prepared for an immediate ambush.
Analyze ISAC Data
Use your ISAC terminal to confirm the presence of biodiesel pollutants used by the Cleaners to create napalm.
Shut Down the Facility
Enter the main production hub, eliminate the local leader, and disable the bio-fuel pumps to stop the contamination.
The biodiesel pollutants are highly flammable. In the water distribution facility, avoid using explosive skills near leaking pipes, as the resulting fire can trap your agent in a corner.
Combat Tactics for Elite Encounters
The campaign missions frequently pit you against elite leaders who use specialized equipment. Success in these encounters depends on your ability to manage your Signature Ability and exploit enemy weaknesses.
Suppressive Fire
- Pin down enemies to prevent flanking.
- Use LMGs for maximum efficiency.
- Allows teammates to move safely.
Signature Timing
- Save for Bosses or Heavy units.
- Look for the "Signature Ready" prompt.
- Coordinate with your squad for max impact.
Cover Usage
- Always find a bed or solid wall.
- Move between cover during reloads.
- Avoid staying in one spot too long.
| Enemy Type | Weak Point | Recommended Weapon | Danger Level |
|---|---|---|---|
| Freeman Pirate | Unarmored Head | Assault Rifle | ★★☆☆☆ |
| Cleaner Tank | Fuel Tank (Back) | Marksman Rifle | ★★★★★ |
| Arms Dealer | Legs/Mobility | SMG | ★★★☆☆ |
| Elite Leader | Armor Plates | Shotgun/Explosives | ★★★★☆ |
When facing the Cleaner leader in the water facility, focus fire on their oxygen and fuel tanks. Rupturing these will cause an explosion that deals massive damage to surrounding minions.
Mission Preparation Checklist
Before embarking on high-level Division Resurgence main missions, ensuring your loadout is optimized is vital. The jump in difficulty between the "Freeman Arc" and the "Cleaner Arc" can be significant if you are under-geared.
Pre-Mission Requirements:
- Check all gear pieces for Armor/Health bonuses
- Equip at least one crowd-control skill (Seeker Mine or Turret)
- Restock medkits and ammunition at the nearest Safe House
- Verify that your Signature Ability is fully charged
- Upgrade your weapon mods to improve stability and range
Completing main missions often rewards you with "Cargo Secured" status, which notifies the JTF for pickup. Always wait for the confirmation before leaving the mission area to ensure you receive the full XP bonus.
Campaign FAQ
Q: How do I unlock more Division Resurgence main missions?
Main missions unlock sequentially as you level up your agent and complete previous story objectives. Some missions also require you to reach a specific 'World Tier' or clear local strongholds first.
Q: Can I replay main missions for better loot?
Yes, once a main mission is cleared, you can replay it on higher difficulty settings (Hard or Heroic) to obtain superior gear and specialized crafting components.
Q: What is the best way to handle the diylene glycol mission?
Focus on speed and environmental awareness. The Cleaners will try to flush you out with fire, so keep moving and use skills like the Chem Launcher to douse flames or heal quickly.
Q: Do I need a group for the campaign missions?
While most missions can be completed solo, the later stages involving faction leaders are significantly easier with a balanced squad of three agents.
Keep an eye on your portable electronic devices (PEDs). They often provide audio logs that reveal the locations of hidden caches within mission zones, providing extra loot for diligent explorers.